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1. Select Target Risk, Scenario, and Media.
Select a pre-defined Target Risk / Target Hazard Quotient or enter a value in the box.
Select one of the land use scenarios under the "Select Scenario" list.
Select one or more media to assess under the "Select Media" list.
2. Select PRG Type.
There are two choices: "Defaults" and "Site Specific".
"Defaults" - calculations will be performed using default toxicity values, chemical-specific parameters, and exposure parameters.
"Site Specific" - there are two options available: "Database Hierarchy Defaults" and "User-provided". In the "Database Hierarchy Defaults" option, only exposure parameters can be edited. The "User-provided" option allows editing of toxicity values and chemical-specific parameters after clicking "Retrieve (new tab)" at the bottom of the form.
3. Select RfD/RfC Type.
Select Chronic or Subchronic for RfD/RfC Type.
Chronic selection will retrieve Chronic-only RfDs/RfCs.
Subchronic selection will retrieve subchronic values (where possible) and then use chronic values.
4. Select Chemicals of Interst.
Select individual Chemicals of Interest by first clicking in the box. Then either scroll through the list or type the chemical name/CAS number. Click on the highlighted name to add it to the list. To add a chemical that is not in the list, type the name of the chemical and click the add button.
Select an entire category of chemicals by clicking one or more options in the "Or Select by Category" list.
Check the "ALL" box to select all chemicals in the database. This is not recommended, and computation time will be affected.
5. Click "Retrieve (new tab)".
After clicking "Retrieve (new tab)" for "Defaults", the results will be presented. Go to step 6.
If "Site-Specific" was selected in step 2, edit exposure parameters (for "Database Hierarchy Defaults") and default toxicity values and chemical-specific parameters (if "User-provided" was selected) in the next window.
At the bottom of this page, click "Retrieve (new tab)" for the results.
Press "Clear" on the bottom of this page to reset all parameters to default values.
6. Review and Export Results.
Input parameters and PRGs for each selected media are presented.
At the top of the final page are options to "Output to XLS" and "Output to PDF".
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