Health Effects Assessment Summary (HEAST) for
Warfarin
CAS: 000081-81-2
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
3E-4 mg/kg/day | |||
| Uncertainty Factor: | 100 | |||
| Route: | Oral | |||
| Target Organ / Critical Effect: | Blood / Increased prothrombin time | |||
| Species | Effect Level | Dose | ||
| Human | LOAEL | 2 mg/day | ||
| References | ||||
| 1985 | Huff B.B., Ed. 1985. Physicians Desk Reference, 39th ed. Medical Economics Co., Inc., Oradell, NJ. | |||
| 1986 | U.S. EPA. 1986. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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