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Health Effects Assessment Summary (HEAST) for
Trinitrotoluene, 2,4,6-
CAS: 000118-96-7
Summary of HEAST Information on-Line
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Subchronic and Chronic Toxicity |
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Carcinogenicity |
Oral [Slope Factor]: | IRIS |
Oral [Unit Risk]: | IRIS |
EPA Group: | IRIS |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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Subchronic [RfD]: (see comment) |
5E-4 mg/kg/day |
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Uncertainty Factor: |
1000 |
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Route: |
Oral: gavage |
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Target Organ / Critical Effect: |
Liver / Effects |
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Species |
Effect Level |
Dose |
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Dog |
LOAEL |
0.5 mg/kg/day |
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References |
1983 | US DOD (Department of Defense). 1983. AD-A157-002. Defense Technical Center, Cameron Station, Alexandria, VA. |
1990 | U.S. EPA. 1990. Health and environmental effects document for 2,4,6-Trinitrotoluene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington DC |
1988 | U.S. EPA. 1988. RfD/RfC Work Group. |
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Subchronic [RfD] Comments: |
The chronic oral RfD was adopted as the subchronic oral [RfD]. |
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