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Health Effects Assessment Summary (HEAST) for

Trinitrotoluene, 2,4,6-

CAS: 000118-96-7


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line
Carcinogenicity
Oral [Slope Factor]:IRIS
Oral [Unit Risk]:IRIS
EPA Group:IRIS






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
5E-4 mg/kg/day

Uncertainty Factor: 1000

Route: Oral: gavage

Target Organ / Critical Effect: Liver / Effects

Species Effect Level Dose
Dog LOAEL 0.5 mg/kg/day

References
1983 US DOD (Department of Defense). 1983. AD-A157-002. Defense Technical Center, Cameron Station, Alexandria, VA.
1990 U.S. EPA. 1990. Health and environmental effects document for 2,4,6-Trinitrotoluene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington DC
1988 U.S. EPA. 1988. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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