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Health Effects Assessment Summary (HEAST) for
Trichloropropane, 1,1,2-
CAS: 000598-77-6
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
5E-2 mg/kg/day |
| Uncertainty Factor: |
300 |
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| Route: |
Oral: drinking water |
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| Target Organ / Critical Effect: |
Liver / Histopathology |
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Kidney / Histopathology |
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Thyroid / Histopathology |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOEL |
100 mg/L |
13 weeks |
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| References |
| 1985 | Villaneuve D.C., I. Chu, V.E. Secours, M.G. Cotie, G.L. Plaa and V.E. Valli. 1985. Results of a 90-day toxicity study on 1,2,3- and 1,1,2-Trichloropropane administered via the drinking water. Sci Total Environ. 47: 421-426. |
| 1987 | U.S. EPA. 1987. RfD/RfC Work Group. |
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