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Health Effects Assessment Summary (HEAST) for

Trichlorophenoxyacetic Acid, 2,4,5-

CAS: 000093-76-5


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 1E-1 mg/kg/day
Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Kidney / Weight effects
Liver / Weight effects

Species Effect Level Dose Experiment Length
Rat NOEL 10 mg/kg/day 90 days

References
1978 Gehring P.J., and J.E. Betso. 1978. Phenoxy Acids: Effects and fate in mammals. Eco Bull. 27: 122-123.
1989 U.S. EPA. 1989. Health effects assessment for 2,4,5-Trichlorophenoxy Acetic Acid. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC



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