Health Effects Assessment Summary (HEAST) for
Trichlorophenoxy) Propionic Acid, 2(2,4,5-
CAS: 000093-72-1
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
8E-3 mg/kg/day | |||
| Uncertainty Factor: | 100 | |||
| Route: | Oral: diet | |||
| Target Organ / Critical Effect: | Liver / Histopathology | |||
| Species | Effect Level | Dose | Experiment Length | |
| Dog | NOEL | 0.75 mg/kg/day | 2 years | |
| References | ||||
| 1978 | Gehring P.J. and J.E. Betso. 1978. Phenoxy Acids: Effects and fate in mammals. In: Chlorinated Phenoxy Acids and their Dioxins. Vol 27. C Ramel Ed. Ecol Bull, Stockholm. pp. 122-133 | |||
| 1966 | Mullison W.R. 1966. Some toxicological aspects of Silvex. In: Proc 19th Ann Meet Southern Weed Conference, Jacksonville, FL. pp. 420-435. | |||
| 1988 | U.S. EPA. 1988. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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