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Health Effects Assessment Summary (HEAST) for

Trichlorophenol, 2,4,5-

CAS: 000095-95-4


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Chronic [RfC]:IRIS






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 1E+0 mg/kg/day
Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Liver / Hepatotoxicity
Kidney / Effects

Species Effect Level Dose Experiment Length
Rat NOEL 1000 ppm 98 days

References
1961 McCollister D.D., D.T. Lockwood and V.K. Rowe. 1961. Toxicologic information on 2,4,5-Trichlorophenol. Toxicol Appl Pharmacol. 3: 63-70.
1984 U.S. EPA. 1984. Health effects assessment for 2,4,5-Trichlorophenol. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC
1987 U.S. EPA. 1987. Health and environmental effects document for Chlorinated Phenols. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1985 U.S. EPA. 1985. RfD/RfC Work Group.



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