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Health Effects Assessment Summary (HEAST) for

Toxaphene

CAS: 008001-35-2


Summary of HEAST Information on-Line

Carcinogenicity
Oral [Slope Factor]:IRIS
Inhalation [Slope Factor]:on-Line
Oral [Unit Risk]:IRIS
Inhalation [Unit Risk]:IRIS
EPA Group:IRIS
Notes/Comments:on-Line






Carcinogenicity

Inhalation [Slope Factor]:
(see comment)
1.1E+0 (mg/kg/day)-1


Route: Oral: diet

Target Organ / Cancer: Liver / Tumors

Species Experiment Length EPA Group
Mouse 18 months IRIS

References
1978 Litton Bionetics, Inc. 1978. Carcinogenic evaluation in mice: Toxaphene. Prepared by Litton Bionetics, Inc., Kensington, MD for Hercules, Inc, Wilmington, DE. LBI project No. 20602.
1987 U.S. EPA. 1987. Health effects assessment for Toxaphene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC.
1980 U.S. EPA. 1980. Ambient Water Quality Criteria document for Toxaphene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Water Regulations and Standards, Washington, DC.
1987 U.S. EPA. 1987. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group.

Inhalation Slope Comment: See Appendix A-II, Dose Conversions on HEAST.



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