Health Effects Assessment Summary (HEAST) for
Toluene-2,5-Diamine
CAS: 000095-70-5
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Chronic [RfD]: (see comment) |
6E-1 mg/kg/day | |||
| Uncertainty Factor: | 100 | |||
| Subchronic [RfD]: (see comment) |
6E-1 mg/kg/day | |||
| Uncertainty Factor: | 100 | |||
| Route: | Oral: diet | |||
| Species | Effect Level | Dose | Experiment Length | |
| Rat | NOAEL | 56 mg/kg/day | 78 weeks | |
| References | ||||
| 1978 | NCI (National Cancer Institute). 1978. Bioassay of Toluene-2,5-diamine Sulfate for possible carcinogenicity. NCI Carcinogenesis Tech Rep Ser No. 126. | |||
| 1984 | U.S. EPA. 1984. Health and environmental effects profile for selected Toluenediamines. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste, Washington, DC | |||
| Subchronic [RfD] Comments: | Determined from data obtained with the sulfate salt. | |||
| Chronic [RfD] Comments: | Determined from data obtained with the Sulfate salt. | |||
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