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Health Effects Assessment Summary (HEAST) for

Tin And Compounds

CAS: 007440-31-5


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:on-Line
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Chronic [RfD]:
(see comment)
6E-1 mg/kg/day

Uncertainty Factor: 100

Subchronic [RfD]:
(see comment)
6E-1 mg/kg/day

Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Liver / Lesions
Kidney / Lesions

Species Effect Level Dose Experiment Length
Rat NOAEL 2000 ppm 2 years

References
1982 NTP (National Toxicology Program). 1982. Carcinogenesis bioassay of Stannous Chloride (CAS No. 7772-99-8) in F344/N rats and B6C3F1/n mice (feed study). NCI/NTP Tech Rep Ser No. 231. Also publ as DHHS (NIH) Publ Iss NIH 82-1787 and NTIS PB 82-242-553
1986 U.S. EPA. 1986. Subchronic (90 day) toxicity of Thallium (I) Sulfate (CAS No. 7446-18-6) in Sprague-Dawley rats. Final report. Environmental Criteria and Assessment Office, Cincinnati, OH. Office of Solid Waste and Emergency Response, Washington, DC
1987 U.S. EPA. 1987. Health effects assessment for Tin. Environmental Criteria and Assessment Office, Cincinnati, OH. Office of Solid Waste and Emergency Response, Washington, DC

Subchronic [RfD] Comments: Calculated by analogy to stannous chloride by correcting for differences in molecular weight.
Chronic [RfD] Comments: Calculated by analogy to stannous chloride by correcting for differences in molecular weight.



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