|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
Chronic [RfD]: (see comment) |
6E-1 mg/kg/day |
|
Uncertainty Factor: |
100 |
|
Subchronic [RfD]: (see comment) |
6E-1 mg/kg/day |
|
Uncertainty Factor: |
100 |
|
Route: |
Oral: diet |
|
Target Organ / Critical Effect: |
Liver / Lesions |
|
Kidney / Lesions |
|
Species |
Effect Level |
Dose |
Experiment Length |
Rat |
NOAEL |
2000 ppm |
2 years |
|
References |
1982 | NTP (National Toxicology Program). 1982. Carcinogenesis bioassay of Stannous Chloride (CAS No. 7772-99-8) in F344/N rats and B6C3F1/n mice (feed study). NCI/NTP Tech Rep Ser No. 231. Also publ as DHHS (NIH) Publ Iss NIH 82-1787 and NTIS PB 82-242-553 |
1986 | U.S. EPA. 1986. Subchronic (90 day) toxicity of Thallium (I) Sulfate (CAS No. 7446-18-6) in Sprague-Dawley rats. Final report. Environmental Criteria and Assessment Office, Cincinnati, OH. Office of Solid Waste and Emergency Response, Washington, DC |
1987 | U.S. EPA. 1987. Health effects assessment for Tin. Environmental Criteria and Assessment Office, Cincinnati, OH. Office of Solid Waste and Emergency Response, Washington, DC |
|
Subchronic [RfD] Comments: |
Calculated by analogy to stannous chloride by correcting for differences in molecular weight. |
Chronic [RfD] Comments: |
Calculated by analogy to stannous chloride by correcting for differences in molecular weight. |
|