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Health Effects Assessment Summary (HEAST) for

Thiram

CAS: 000137-26-8


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 6E-3 mg/kg/day
Uncertainty Factor: 100

Route: Oral

Target Organ / Critical Effect: Reproduction / Impaired

Species Effect Level Dose Experiment Length
Ferret NOAEL 0.61 mg/kg/day 24 weeks

References
1987 Hornshaw T.C., R.J. Aulerich and R.K. Ringer. 1987. Toxicity of Thiram (Tetramethylthinoram Disulfide) to mink and European ferrets. Bull Environ Contam Toxicol. 38(4): 618-626.
1989 U.S. EPA. 1989. Health and environmental effects document for Thiram. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC



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