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Health Effects Assessment Summary (HEAST) for

Thallium (I) Carbonate

CAS: 006533-73-9


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
8E-4 mg/kg/day

Uncertainty Factor: 300

Route: Oral

Target Organ / Critical Effect: Liver / Increased SGOT
Blood / Increased serum LDH
Hair / Alopecia

Species Effect Level Dose Experiment Length
Rat NOAEL 0.23 mg/kg/day 90 days

References
1986 U.S. EPA. 1986. Subchronic (90 day) toxicity of Thallium (I) Sulfate (CAS No. 7446-18-6) in Sprague-Dawley rats. Final report. Environmental Criteria and Assessment Office, Cincinnati, OH Office of Solid Waste and Emergency Response, Washington, DC
1988 U.S. EPA. 1988. Health and environmental effects document for Thallium and compounds. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1988 U.S. EPA. 1988. RfD/RfC Work Group.

Subchronic [RfD] Comments: Calculated by analogy to Thallium (I) Sulfate by correcting for molecular weight differences.



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