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Health Effects Assessment Summary (HEAST) for

Tetraethyl Dithiopyrophosphate

CAS: 003689-24-5

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 5E-3 mg/kg/day
Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Erythrocytes / Decreased cholinesterase activity
Blood / Decreased cholinesterase activity

Species Effect Level Dose Experiment Length
Rat NOEL 0.5 mg/kg/day 3 months

References
1974 Kimmerle G. and O.R. Klimmer. 1974. Acute and subchronic toxicity of Sulfotep. Arch Toxicol. 33(1): 1-16.
1988 U.S. EPA. 1988. RfD/RfC Work Group.


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