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Health Effects Assessment Summary (HEAST) for

Tetrachlorophenol, 2,3,4,6-

CAS: 000058-90-2

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 3E-1 mg/kg/day
Uncertainty Factor: 100

Route: Oral: gavage

Target Organ / Critical Effect: Liver / Increased weight
Liver / Centrilobular hypertrophy

Species Effect Level Dose Experiment Length
Rat NOAEL 25 mg/kg/day 90 days

References
1986 U.S. EPA. 1986. 2,3,4,6-Tetrachlorophenol, 90-day subchronic oral toxicity study in rats. Office of Solid Waste, Washington, DC


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