EPA Home PageSuperfund Risk Assessment Home Page


Health Effects Assessment Summary (HEAST) for

Tetrachloroethane, 1,1,2,2-

CAS: 000079-34-5


Summary of HEAST Information on-Line

Carcinogenicity
Oral [Slope Factor]:IRIS
Inhalation [Slope Factor]:on-Line
Oral [Unit Risk]:IRIS
Inhalation [Unit Risk]:IRIS
EPA Group:IRIS
Notes/Comments:on-Line






Carcinogenicity

Inhalation [Slope Factor]:
(see comment)
2.0E-1 (mg/kg/day)-1


Route: Oral: gavage

Target Organ / Cancer: Liver / Carcinoma

Species Experiment Length EPA Group
Mouse 75 weeks IRIS

References
1978 NCI (National Cancer Institute). 1978. Bioassay of 1,1,2,2-Tetrachloroethane for possible carcinogenicity. NCI Carcinogenesis Tech Rep Ser No. 27, DHEW No. (NIH) 78-827.
1980 U.S. EPA. 1980. Ambient Water Quality Criteria document for Chlorinated Ethanes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Water Regulations and Standards, Washington, DC.
1986 U.S. EPA. 1986. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group.

Inhalation Slope Comment: Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST.



[ Risk Assessment Home ]
[ EPA Home | OSWER Home | Superfund Home ]
[ Search EPA | Search Superfund | Whats New | Contact Us ]

Horizontal Rule
URL: http://risk.lsd.ornl.gov/epa/heast/heast_select.htm
This page was last updated on: March 1, 2000
Site maintained by: Office of Emergency and Remedial Response
Hofmann.Lee@epamail.epa.gov

Horizontal Rule