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Health Effects Assessment Summary (HEAST) for
Tetrachloroethane, 1,1,2,2-
CAS: 000079-34-5
Summary of HEAST Information on-Line
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Carcinogenicity |
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Carcinogenicity |
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Inhalation [Slope Factor]: (see comment) | 2.0E-1 (mg/kg/day)-1 |
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Route: |
Oral: gavage |
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Target Organ / Cancer: |
Liver / Carcinoma |
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Species |
Experiment Length |
EPA Group |
Mouse |
75 weeks |
IRIS |
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References |
1978 | NCI (National Cancer Institute). 1978. Bioassay of 1,1,2,2-Tetrachloroethane for possible carcinogenicity. NCI Carcinogenesis Tech Rep Ser No. 27, DHEW No. (NIH) 78-827. |
1980 | U.S. EPA. 1980. Ambient Water Quality Criteria document for Chlorinated Ethanes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Water Regulations and Standards, Washington, DC. |
1986 | U.S. EPA. 1986. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. |
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Inhalation Slope Comment: |
Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST. |
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