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Health Effects Assessment Summary (HEAST) for
Tetrachlorobenzene, 1,2,4,5-
CAS: 000095-94-3
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
3E-3 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: diet |
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| Target Organ / Critical Effect: |
Kidney / Lesions |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
0.34 mg/kg/day |
13 weeks |
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| References |
| 1984 | Chu I., D.C. Villeneuve, V.E. Valli and V.E. Secours. 1984. Toxicity of 1,2,3,4-, 1,2,3,5- and 1,2,4,5-Tetrachlorobenzene in the rat: Results of a 90-day feeding study. Drug Chem Toxicol. 7: 113-127. |
| 1985 | U.S. EPA. 1985. RfD/RfC Work Group. |
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