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Health Effects Assessment Summary (HEAST) for

Styrene

CAS: 000100-42-5

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Chronic [RfC]:IRIS
Subchronic [RfC]:on-Line
Carcinogenicity
Notes/Comments:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfC]: 3E+0 mg/cu m
Uncertainty Factor: 10

Route: Inhalation: occupational

Target Organ / Critical Effect: Central nervous system / Effects

Species Effect Level Dose
Human NOAEL 22 ppm

References
1984 Mutti A., A. Mazzucchi, P. Rustichelli, G. Frizeri, G. Arfini, I. Franchini. 1984. Exposure effect and exposure response. The relationship between occupational exposure to Styrene and neuropsychological function. Amer J Ind Med. 5: 275-286.
1992 U.S. EPA. 1992. RfD/RfC Work Group.





Carcinogenicity

General Comment: Contact the Superfund Health Risk Technical Support Center: (513) 569-7300.


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