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Health Effects Assessment Summary (HEAST) for

Strychnine

CAS: 000057-24-9

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 3E-3 mg/kg/day
Uncertainty Factor: 1000

Route: Oral: gavage

Target Organ / Critical Effect: Unspecified / Toxicity
Unspecified / Histopathology

Species Effect Level Dose Experiment Length
Rat LOAEL 2.5 mg/kg/day 28 days

References
1982 Seidl I. and G. Zbinden. 1982. Subchronic oral toxicity of Strychnine in rats. Arch Toxicol. 51(3): 267-271.
1985 U.S. EPA. 1985. RfD/RfC Work Group.
General Comments: The LOAEL is also the FEL.


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