Health Effects Assessment Summary (HEAST) for
Sodium Cyanide
CAS: 000143-33-9
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
4E-2 mg/kg/day | |||
| Uncertainty Factor: | 500 | |||
| Route: | Oral: diet | |||
| Target Organ / Critical Effect: | Central nervous system / Effects | |||
| Species | Effect Level | Dose | ||
| Rat | NOAEL | 20.4 mg/kg/day | ||
| References | ||||
| 1955 | Howard J.W. and R.F. Hanzal. 1955. Chronic toxicity for rats of food treated with Hydrogen Cyanide. J Agric Food Chem. 3: 325-329. Cited in U.S. EPA, 1985. | |||
| 1984 | U.S. EPA. 1984. Health effects assessment for Sodium Cyanide. Environmental Criteria and Assessment Office, Cincinnati, OH. Office of Emergency and Remedial Response, Washington, DC | |||
| 1985 | U.S. EPA. 1985. Integrated Risk Information System (IRIS): Reference dose (RfD) for oral exposure for Sodium Cyanide. Environmental Criteria and Assessment Office. Cincinnati, OH. | |||
| 1985 | U.S. EPA. 1985. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | Calculated by analogy to free cyanide by correcting for differences in molecular weight. The oral chronic RfD was adopted as the subchronic oral [RfD]. | |||
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