Health Effects Assessment Summary (HEAST) for
Selenium
CAS: 007782-49-2
| Summary of HEAST Information on-Line | ||||||
| Subchronic and Chronic Toxicity | ||||||
|
| Subchronic [RfD]: (see comment) |
5E-3 mg/kg/day | |||
| Uncertainty Factor: | 3 | |||
| Route: | Oral: diet | |||
| Target Organ / Critical Effect: | Whole body / Selenosis, clinical | |||
| Species | Effect Level | Dose | ||
| Human | NOAEL | 0.853 mg/day | ||
| References | ||||
| 1989 | Yang G., S. Yin, L. Zhou, et al. 1989. Studies of safe maximal daily dietary Se-intake in a seleniferous area in China. II. Relation between Se-intake and the manifestation of clinical signs and certain biochemical alterations in blood and urine. J Trace Elem Electrolytes Health Dis. 3: 123-130. | |||
| 1989 | U.S. EPA. 1989. Health and environmental effects document for Selenium and compounds. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC | |||
| 1991 | U.S. EPA. 1991. RfD/RfC Work Group. | |||
| Subchronic [RfD] Comments: | The chronic oral RfD was adopted as the subchronic oral [RfD]. | |||
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