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Health Effects Assessment Summary (HEAST) for

Pyridine

CAS: 000110-86-1

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 1E-2 mg/kg/day
Uncertainty Factor: 100

Route: Oral: gavage

Target Organ / Critical Effect: Liver / Increased weight
Liver / Increased relative weight

Species Effect Level Dose Experiment Length
Rat NOAEL 1 mg/kg/day 90 days

References
1986 U.S. EPA. 1986. Pyridine. 90-day subchronic oral toxicity in rats. Sponsored by Office of Solid Waste, Washington, DC
1986 U.S. EPA. 1986. Health and environmental effects profile for Pyridine. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste, Washington, DC
1987 U.S. EPA. 1987. RfD/RfC Work Group.


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