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Health Effects Assessment Summary (HEAST) for
Phenylenediamine, m-
CAS: 000108-45-2
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Subchronic [RfD]: |
6E-2 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral |
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| Target Organ / Critical Effect: |
Liver / Lesions |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOEL |
6 mg/kg/day |
90 days |
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| References |
| 1982 | Hofer H and R Hruby. 1982. Ninety-day toxicity study with m-Phenylenediamine on rats. Oesterr Forschungszent Seibersdorf (Ber.) Oefzs Ber. No. 4155. P 50. |
| 1985 | U.S. EPA. 1985. Health and environmental effects profile for Phenylenediamines (o-, m-, p-). Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
| 1986 | U.S. EPA. 1986. RfD/RfC Work Group. |
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