EPA Home PageSuperfund Risk Assessment Home Page


Health Effects Assessment Summary (HEAST) for

Pentachlorobenzene

CAS: 000608-93-5

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 8E-3 mg/kg/day
Uncertainty Factor: 1000

Route: Oral: diet

Target Organ / Critical Effect: Liver / Toxicity
Kidney / Toxicity

Species Effect Level Dose Experiment Length
Rat LOAEL 8.3 mg/kg/day 100 days

References
1980 Linder R., T. Scotti J. Goldstein and K. McElroy. 1980. Acute and subchronic toxicity of Pentachlorobenzene. J Environ Pathol Toxicol. 4(5-6): 183-196.
1989 U.S. EPA. 1989. Health and environmental effects document for Pentachlorobenzene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1985 U.S. EPA. 1985. RfD/RfC Work Group.


[ Risk Assessment Home ]
[ EPA Home | OSWER Home | Superfund Home ]
[ Search EPA | Search Superfund | Whats New | Contact Us ]
Horizontal Rule
URL: http://risk.lsd.ornl.gov/epa/heast/heast_select.htm
This page was last updated on: March 1, 2000
Site maintained by: Office of Emergency and Remedial Response
Hofmann.Lee@epamail.epa.gov
Horizontal Rule