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Health Effects Assessment Summary (HEAST) for

Pentabromo-6-Chlorocyclohexane, 1,2,3,4,5-

CAS: 000087-84-3


Summary of HEAST Information on-Line

Carcinogenicity
Oral [Slope Factor]:on-Line
Oral [Unit Risk]:on-Line
EPA Group:on-Line
Notes/Comments:on-Line






Carcinogenicity

Oral [Slope Factor]:
(see comment)
2.3E-2 (mg/kg/day)-1


Oral [Unit Risk]: 6.6E-7 (µg/L)-1

Route: Oral: diet

Target Organ / Cancer: Intestine, large / Tumors

Species Experiment Length EPA Group
Rat 2 years C

References
1981 Blair E.H. 1981. TSCA Sec 8(e) submission 8EHQ-0381-0393, 88-8100295 by Dow Chemical Co. Office of Toxic Substances, U.S. EPA, Washington, DC.
1985 U.S. EPA. 1985. Health and environmental effects profile for 1,2,3,4,5-Pentabromo-6-chlorocyclohexane. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC.

Oral Slope Comment: Based on results with the alpha isomer.



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