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Health Effects Assessment Summary (HEAST) for

Pendimethalin

CAS: 040487-42-1


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
4E-2 mg/kg/day

Uncertainty Factor: 300

Route: Oral: capsule

Target Organ / Critical Effect: Liver / Effects

Species Effect Level Dose Experiment Length
Dog NOEL 12.5 mg/kg/day 2 years

References
1979 American Cyanamid Company. 1979. Confidential business information, unpublished study. MRID No. 0058657. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for Pendimethalin. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste, Washington, DC
1987 U.S. EPA. 1987. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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