Health Effects Assessment Summary (HEAST) for
Nitrosopyrrolidine, n-
CAS: 000930-55-2
| Summary of HEAST Information on-Line | ||||||||||||
| Carcinogenicity | ||||||||||||
|
| Inhalation [Slope Factor]: (see comment) | 2.1E+0 (mg/kg/day)-1 | |||
| Route: | Oral: diet | |||
| Target Organ / Cancer: | Liver / Tumors | |||
| Species | Experiment Length | EPA Group | ||
| Rat | Lifetime | IRIS | ||
| References | ||||
| 1977 | Preussman R., D. Schmahl and G. Eisenbrand. 1977. Carcinogenicity of n-Nitrosopyrrolidine: dose-response study in rats. Z Krebsforsch. 90: 161-166. | |||
| 1986 | U.S. EPA. 1986. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. | |||
| Inhalation Slope Comment: | Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST. | |||
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