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Health Effects Assessment Summary (HEAST) for
Nitroso-n-Methylurea, n-
CAS: 000684-93-5
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Summary of HEAST Information on-Line
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| Carcinogenicity |
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Carcinogenicity |
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| Route: |
Oral: gavage |
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| Target Organ / Cancer: |
Pancreas / Adenocarcinoma |
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| Species |
Experiment Length |
EPA Group |
| Guniea pig |
308 days |
B2 |
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| References |
| 1975 | Reddy, J.K. and M.S. Rao. 1975. Pancreatic adenocarcinoma in inbred guinea pigs induced by n-Methyl-n-nitrosourea. Cancer Res. 35: 2269-2277. |
| 1988 | U.S. EPA. 1988. Evaluation of the potential carcinogenicity of n-Nitroso-n-methylurea. In support of reportable quantity adjustments pursuant to CERCLA Section 102. Prepared by the Carcinogen Assessment Group, Office of Health and Environmental Assessment, Washington, DC for the Office of Emergency and Remedial Response, Office of Solid Waste and Emergency Response, Washington, DC. |
| 1992 | U.S. EPA. 1992. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. |
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| General Comment: |
The CRAVE work group states (04-01-92) that there is no acceptable quantitation for Nitroso-n-Methylurea. |
| EPA Group Comment: |
Under review, classification subject to change. |
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