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Health Effects Assessment Summary (HEAST) for
Nitroso-n-Ethylurea, n-
CAS: 000759-73-9
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Summary of HEAST Information on-Line
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| Carcinogenicity |
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Carcinogenicity |
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| Oral [Slope Factor]: |
1.4E+2 (mg/kg/day)-1 |
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| Route: |
Oral: drinking water |
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| Target Organ / Cancer: |
Intestine / Gastrointestinal tumors |
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| Species |
Experiment Length |
EPA Group |
| Rat |
203 days |
B2 |
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| References |
| 1979 | Bulay, O., S.S. Mirvish, H. Garcia, A.F. Pelfrene, B. Gold and M. Eagan. 1979. Carcinogenicity tests of six Nitrosamides and Nitrosocyanamide administered orally to rats. J Natl Cancer Inst. 62: 1523-1528. |
| 1988 | U.S. EPA. 1988. Evaluation of the potential carcinogenicity of n-Nitroso-n-ethylurea. In support of reportable quantity adjustments pursuant to CERCLA Section 102. Prepared by the Carcinogen Assessment Group, Office of Health and Environmental Assessment, Washington, DC for the Office of Emergency and Remedial Response, Office of Solid Waste and Emergency Response, Washington, DC. |
| 1987 | U.S. EPA. 1987. Carcinogen Risk Assessment Verification (CRAVE) Work Group. |
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| EPA Group Comment: |
Under review, classification subject to change. |
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