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Health Effects Assessment Summary (HEAST) for
Nitroaniline, 2-
CAS: 000088-74-4
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Chronic [RfC]: |
2E-4 mg/cu m |
| Uncertainty Factor: |
10000 |
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| Subchronic [RfC]: |
2E-3 mg/cu m |
| Uncertainty Factor: |
1000 |
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| Route: |
Inhalation: intermittent |
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| Target Organ / Critical Effect: |
Blood / Hematological effects |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
LOAEL |
9.8 mg/cu m |
4 weeks |
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| References |
| 1983 | Bio/Dynamics. 1983. Project No. (BD-82-270). A four week inhalation study of ortho-Nitroaniline in male rats. Final report. Submitted to Dr. Rashmi Nair, Monsanto CO., August 16, 1983. EPA 87821478. #OTS0206486. P. 1a-17, 32-42, 46-48, 55-58, 62-67. |
| 1985 | U.S. EPA. 1985. Health and environmental effects profile for Nitroaniline (o-, m-, p-). Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
| 1991 | U.S. EPA. 1991. Health and environmental effects document for 2-Nitroaniline. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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