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Health Effects Assessment Summary (HEAST) for

Nickel Refinery Dust

CAS: CURENO-07-3


Summary of HEAST Information on-Line

Carcinogenicity
Inhalation [Slope Factor]:on-Line
Inhalation [Unit Risk]:IRIS
EPA Group:IRIS
Notes/Comments:on-Line






Carcinogenicity

Inhalation [Slope Factor]:
(see comment)
8.4E-1 (mg/kg/day)-1


Route: Inhalation: occupational

Target Organ / Cancer: Respiratory system / Tumors

Species EPA Group
Human IRIS

References
1981 Chovil, A., R.B. Sutherland and M. Halliday. 1981. Respiratory cancer in a cohort of Nickel sinter plant workers. Br J Ind Med. 38: 327-333.
1984 Peto, J., H. Cuckle, R. Dool, et al. 1984. Respiratory cancer mortality of Welsh Nickel refinery workers. In: Nickel in the human environment: Proceedings of a joint symposium, March, 1983. Larc Scientific Publ No. 53, IARC, Lyon, France. P. 36-46.
1982 Enterline, P.E. and G.M. Marsh. 1982. Mortality among workers in a Nickel refinery and alloy manufacturing plant in West Virginia. J Nat Cancer Inst 68: 925-933.
1982 Magnus, K., A. Andersen and A. Hogetveit. 1982. Cancer of respiratory organs among workers at a Nickel refinery in Norway. Int J Cancer. 30: 681-685.
1985 U.S. EPA. 1985. Health assessment document for Nickel. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Research Triangle Park, NC.
1987 U.S. EPA. 1987. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group.

General Comment: Formerly listed as Nickel.
Inhalation Slope Comment: See Appendix A-II, Dose Conversions on HEAST.



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