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Health Effects Assessment Summary (HEAST) for

Molybdenum

CAS: 007439-98-7


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
5E-3 mg/kg/day

Uncertainty Factor: 30

Route: Oral: water, diet

Target Organ / Critical Effect: Urine / Increased uric acid
Joints / Pain, swelling
Blood / Decreased copper levels

Species Effect Level Dose
Human LOAEL 0.14 mg/kg/day

References
1961 Kolval'skiy V.V., G.A. Yarovaya and D.M. Shmavonyan. 1961. Changes of purine metabolism in man and animals under conditions of Molybdenum biogeochemical provinces. Zh Obshch Biol. 22: 179-191. (in Russian, translation)
1991 U.S. EPA. 1991. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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