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Health Effects Assessment Summary (HEAST) for
Methylaniline Hydrochloride, 2-
CAS: 000636-21-5
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Summary of HEAST Information on-Line
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| Carcinogenicity |
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Carcinogenicity |
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| Oral [Slope Factor]: |
1.8E-1 (mg/kg/day)-1 |
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| Oral [Unit Risk]: |
5.1E-6 (µg/L)-1 |
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| Route: |
Oral: diet |
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| Target Organ / Cancer: |
Skin / Fibroma |
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| Species |
Experiment Length |
EPA Group |
| Rat |
93 weeks |
B2 |
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| References |
| 1982 | Hecht S.S., A. El-Boyoumy, A. Rivenson and E. Fiala. 1982. Comparative carcinogenicity of o-Toluidine Hydrochloride and o-Nitrosotoluene in F-344 rats. Cancer Lett. 16(1): 103-108. |
| 1987 | U.S. EPA. 1987. Health and environmental effects profile for 2-Methylaniline and 2-Methylaniline Hydrochloride. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. |
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