EPA Home PageSuperfund Risk Assessment Home Page


Health Effects Assessment Summary (HEAST) for

Methanol

CAS: 000067-56-1

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 5E+0 mg/kg/day
Uncertainty Factor: 100

Route: Oral: gavage

Target Organ / Critical Effect: Blood / Increased alkaline phosphatase
Blood / Increased SGPT
Brain / Decreased weight

Species Effect Level Dose Experiment Length
Rat NOEL 500 mg/kg/day 90 days

References
1986 U.S. EPA. 1986. Rat oral subchronic toxicity study with Methanol. Office of Solid Waste. Washington, DC
1988 U.S. EPA. 1988. RfD/RfC Work Group.


[ Risk Assessment Home ]
[ EPA Home | OSWER Home | Superfund Home ]
[ Search EPA | Search Superfund | Whats New | Contact Us ]
Horizontal Rule
URL: http://risk.lsd.ornl.gov/epa/heast/heast_select.htm
This page was last updated on: March 1, 2000
Site maintained by: Office of Emergency and Remedial Response
Hofmann.Lee@epamail.epa.gov
Horizontal Rule