|
|
|
|
Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
|
| Subchronic [RfD]: |
3E-3 mg/kg/day |
| Uncertainty Factor: |
1000 |
|
| Route: |
Oral: subcutaneous |
|
| Target Organ / Critical Effect: |
Immune system / Autoimmune effects |
|
| Species |
| | |
| Rat |
| | |
|
| References |
| 1984 | Andres P. 1984. IGA-IGG disease in the intestine of Brown-Norway rats ingesting Mercuric Chloride. Clin Immunol Immunopathol. 20: 488-494. |
| 1981 | Bernaudin J.F., E. Druet, P. Druet, R. Masse. 1981. Inhalation or ingestion of organic or in organic Mercurials produces auto-immune disease in rats. Clin Immunol Immunopathol. 20: 129-135. |
| 1978 | Druet P., E. Druet, F. Potdevin, C. Sapin. 1978. Immune type glomerulonephritis induces by Hg Cl2 in the Brown-Norway rat. Ann Immunol. 129c: 777-792. |
| 1987 | U.S. EPA. 1987. Peer review workshop on Mercury issues, October 26-27, 1987. Environmental Criteria and Assessment Office, Cincinnati, OH. |
| 1988 | U.S. EPA. 1988. RfD/RfC Work Group. |
| 1995 | U.S. EPA. 1995. Mercury study report to congress. Office of Research and Development. Washington, DC, External review draft. EPA/600/P-94/002AB. |
|
