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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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Subchronic [RfD]: (see comment) |
5E-1 mg/kg/day |
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Uncertainty Factor: |
1000 |
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Route: |
Oral: diet |
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Target Organ / Critical Effect: |
Kidney / Altered function |
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Species |
Effect Level |
Dose |
Experiment Length |
Rat |
LOAEL |
500 mg/kg/day |
28 months |
|
References |
1981 | Uniroyal Chemical Co. 1981. Accession No. 250523. |
1989 | U.S. EPA. 1989. Health and environmental effects document for Maleic Anhydride. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
1986 | U.S. EPA. 1986. RfD/RfC Work Group. |
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Subchronic [RfD] Comments: |
The chronic oral RfD was adopted as the subchronic oral [RfD]. |
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