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Health Effects Assessment Summary (HEAST) for

Linuron

CAS: 000330-55-2

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line
Carcinogenicity
EPA Group:IRIS





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)		 2E-3 mg/kg/day

Uncertainty Factor: 300

Route: Oral: diet

Target Organ / Critical Effect: Blood / Hematological effects

Species Effect Level Dose Experiment Length
Dog LOAEL 0.625 mg/kg/day 2 years

References
1962 Du Pont de Nemours and Company, Inc. 1962. Confidential business information, unpublished study. MRID No. 00018374. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for Linuron. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.
Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].


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