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Health Effects Assessment Summary (HEAST) for
Hydrogen Sulfide
CAS: 007783-06-4
Summary of HEAST Information on-Line
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Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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Subchronic [RfD]: |
3E-2 mg/kg/day |
Uncertainty Factor: |
100 |
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Route: |
Oral: food |
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Target Organ / Critical Effect: |
Gastrointestinal system / Disturbance |
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Species |
Effect Level |
Dose |
Experiment Length |
Pig |
NOAEL |
3.1 mg/kg/day |
105 days |
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References |
1964 | Watterau H., W. Oeckert and U.G. Knape. 1964. Tests for the application of dried green fodder with high H2S content (experiments with poultry and fattened pigs). Lettin Feeds Testing Center and Feeding Hall. Feeds Science. Fetterung. 5: 383-393. |
1985 | U.S. EPA. 1985. RfD/RfC Work Group. |
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Subchronic [RfC]: |
1E-2 mg/cu m |
Uncertainty Factor: |
100 |
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Route: |
Inhalation: intermittent |
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Target Organ / Critical Effect: |
Nasal mucosa / Inflammation |
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Species |
Effect Level |
Dose |
Experiment Length |
Mouse |
NOAEL |
42 mg/cu m |
13 weeks |
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References |
1983 | CIIT. 1983. 90 day vapor inhalation toxicity study of Hydrogen Sulfide in B6C3F1 mice. EPA OTS public files. Fiche No. 0000255-0. Document No. FYI-OTS-0883-0255. |
1990 | U.S. EPA. 1990. Health and environmental effects document for Hydrogen Sulfide. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH, for the Office of Solid Waste and Emergency Response, Washington, DC |
1995 | U.S. EPA. 1995. RfD/RfC Work Group. |
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