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Carcinogenicity |
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Inhalation [Slope Factor]: (see comment) | 1.7E+1 (mg/kg/day)-1 |
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Route: |
Inhalation: intermittent |
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Target Organ / Cancer: |
Nasal cavity / Tumors |
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Species |
Experiment Length |
EPA Group |
Rat |
1 year |
IRIS |
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References |
1981 | Macewen J.D., E.H. Vernot, C.C. Haun, E.R. Kinkead and A. Hall, III. 1981. Chronic inhalation toxicity of Hydrazine: oncogenic effects. Air Force Aerospace Medical Research Laboratory, Wright-Patterson Air Force Base, OH. |
1984 | U.S. EPA. 1984. Health and environmental effects profile for Hydrazine and Hydrazine Sulfate. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. |
1987 | U.S. EPA. 1987. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. |
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General Comment: |
Listed under "Hydrazine" on IRIS. |
Inhalation Slope Comment: |
See Appendix A-II, Dose Conversions on HEAST. |
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