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Carcinogenicity |
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Inhalation [Slope Factor]: (see comment) | 1.8E+0 (mg/kg/day)-1 |
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Route: |
Oral: diet |
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Target Organ / Cancer: |
Liver / Tumors |
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Species |
Experiment Length |
EPA Group |
Mouse |
6-20 months |
IRIS |
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References |
1983 | Munir K.M., C.S. Soman and V. Sumati. 1983. Hexachlorocyclohexane-induced tumorigenicity in mice under different experimental conditions. Tumorigenicity. 69: 383-386. |
1987 | U.S. EPA. 1987. Health and environmental effects profile for Hexachlorocyclohexanes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. |
1986 | U.S. EPA. 1986. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group. |
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Inhalation Slope Comment: |
Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST. |
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