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Health Effects Assessment Summary (HEAST) for

Hexachlorocyclohexane, Beta-

CAS: 000319-85-7


Summary of HEAST Information on-Line

Carcinogenicity
Oral [Slope Factor]:IRIS
Inhalation [Slope Factor]:on-Line
Oral [Unit Risk]:IRIS
Inhalation [Unit Risk]:IRIS
EPA Group:IRIS
Notes/Comments:on-Line






Carcinogenicity

Inhalation [Slope Factor]:
(see comment)
1.8E+0 (mg/kg/day)-1


Route: Oral: diet

Target Organ / Cancer: Liver / Tumors

Species Experiment Length EPA Group
Mouse 110 weeks IRIS

References
1973 Thorpe E. and A.I.T. Walker. 1973. Toxicology of Dieldrin (HEOD). II. Comparative long-term oral toxicity studies in mice with Dieldrin, DDT, Phenobarbitone, beta-HCH and gamma-HCH. Food Cosmet Toxicol. 11: 433-442.
1987 U.S. EPA. 1987. Health and environmental effects profile for Hexachlorocyclohexanes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC.
1987 U.S. EPA. 1987. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group.

Inhalation Slope Comment: Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST.



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