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Health Effects Assessment Summary (HEAST) for

Hexachlorobenzene

CAS: 000118-74-1

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Chronic [RfC]:IRIS
Carcinogenicity
Oral [Slope Factor]:IRIS
Inhalation [Slope Factor]:on-Line
Oral [Unit Risk]:IRIS
Inhalation [Unit Risk]:IRIS
EPA Group:IRIS
Notes/Comments:on-Line





Carcinogenicity
Inhalation [Slope Factor]:
(see comment)		1.6E+0 (mg/kg/day)-1


Route: Oral: diet

Target Organ / Cancer: Liver / Tumors

Species EPA Group
Rat IRIS

References
1986 Erturk E., R.W. Lambrecht, H.A. Peters, D.J. Cripps et al. 1986. Oncogenicity of Hexachlorobenzene. In: Hexachlorobenzene: Proc Int Symp, C.R. Morris and J.R.P. Cabral, ed. Larc Scientific Publ No. 77, Oxford University Press, Oxford. P. 417-423.
1991 U.S. EPA. 1991. Drinking water criteria document for Hexachlorobenzene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Drinking Water, Washington, DC.
1984 U.S. EPA. 1984. Health effects assessment for Hexachlorobenzene. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC.
1989 U.S. EPA. 1989. Carcinogen Risk Assessment Verification Endeavor (CRAVE) Work Group.
Inhalation Slope Comment: Based on route to route extrapolation. See Appendix A-II, Dose Conversions on HEAST.


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