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Health Effects Assessment Summary (HEAST) for

Hexabromobenzene

CAS: 000087-82-1

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 2E-2 mg/kg/day
Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Liver / Induced carboxylesterase activity

Species Effect Level Dose Experiment Length
Rat NOAEL 2 mg/kg/day 12 weeks

References
1977 Mendoza C.E., H.M. Vijay, J.B. Shields and G.W. Laver. 1977. Effects of Hexabromobenzene on the male rat. Toxicol Appl Pharmacol. 41: 127-130.
1984 U.S. EPA. 1984. Health and environmental effects profile for Bromobenzenes. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste, Washington, DC
1985 U.S. EPA. 1985. RfD/RfC Work Group.


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