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Health Effects Assessment Summary (HEAST) for

Glycidaldehyde

CAS: 000765-34-4

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Chronic [RfC]:on-Line
Subchronic [RfC]:on-Line
Notes/Comments:on-Line
Carcinogenicity
EPA Group:IRIS





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)		 4E-3 mg/kg/day

Uncertainty Factor: 300

Chronic [RfC]: 1E-3 mg/cu m
Uncertainty Factor: 3000

Subchronic [RfC]: 1E-2 mg/cu m
Uncertainty Factor: 300

Route: Inhalation: intermittent

Target Organ / Critical Effect: Whole body / Decreased weight
Kidney / Effects

Species Effect Level Dose Experiment Length
Rat NOAEL 29 mg/cu m 12 weeks

References
1961 Hine C.H., R.J. Guzman, M.K. Dunlap, R. Lima and G.S. Loquvam. 1961. Studies on the toxicity of Glycidaldehyde. Arch Environ Health. 2: 23-30.
1989 U.S. EPA. 1989. Health and environmental effects document for Glycidaldehyde. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1987 U.S. EPA. 1987. RfD/RfC Work Group.
Subchronic [RfD] Comments: Based on route to route extrapolation using an absorption factor of 0.5.


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