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Health Effects Assessment Summary (HEAST) for

Fluridone

CAS: 059756-60-4

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)		 8E-2 mg/kg/day

Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Kidney / Glomerulonephritis
Testis / Atrophy
Whole body / Decreased weight
Organs / Decreased weight

Species Effect Level Dose Experiment Length
Rat NOEL 200 ppm 2 years

References
1980 Elanco Products Company, division of Eli Lilly and Company. 1980. Confidential business information, unpublished study. Accession Nos. 070933, 070939. MRID No. 00103251, 00103305. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1984 U.S. EPA. 1984. Health and environmental effects profile for Fluridone. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC
1988 U.S. EPA. 1988. RfD/RfC Work Group.
Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].


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