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Health Effects Assessment Summary (HEAST) for

Ethylene Glycol Monobutyl Ether

CAS: 000111-76-2


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfC]:on-Line
Subchronic [RfC]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Chronic [RfC]:
(see comment)
2E-2 mg/cu m

Uncertainty Factor: 1000

Subchronic [RfC]: 2E-1 mg/cu m
Uncertainty Factor: 100

Route: Inhalation: intermittent

Target Organ / Critical Effect: Blood / Altered hematology

Species Effect Level Dose Experiment Length
Rat NOAEL 121 mg/cu m 13 weeks

References
1983 Dodd D.E., W.M. Snellings, R.R. Marompot, et al. 1983. Ethylene Glycol Monobutyl Ether: Acute, 9-day and 90-day vapor inhalation studies in Fischer 344 rats. Toxicol Appl Pharmacol. 68: 405-414.
1991 U.S. EPA. 1991. RfD/RfC Work Group.

Chronic [RfC] Comments: Under review, current number subject to change.



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