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Health Effects Assessment Summary (HEAST) for
Ethylene Diamine
CAS: 000107-15-3
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Chronic [RfD]: |
2E-2 mg/kg/day |
| Uncertainty Factor: |
1000 |
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| Subchronic [RfD]: |
2E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: diet |
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| Target Organ / Critical Effect: |
Heart / Decreased weight |
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Blood / Hematologic changes |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOAEL |
22.6 mg/kg/day |
3 months |
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| References |
| 1983 | Yang R.S., R.H. Garman, R.R. Maronpot, et al. 1983. Acute and subchronic toxicity of Ethylenediamine in laboratory animals. Fund Appl Toxicol. 3(6): 512-520. |
| 1988 | U.S. EPA. 1988. Health and environmental effects document for Ethylenediamine. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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