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Health Effects Assessment Summary (HEAST) for
Ethylene Cyanohydrin
CAS: 000109-78-4
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Summary of HEAST Information on-Line
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| Subchronic and Chronic Toxicity |
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Subchronic and Chronic Toxicity
(Other than Carcinogenicity) |
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| Chronic [RfD]: |
3E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Subchronic [RfD]: |
3E-1 mg/kg/day |
| Uncertainty Factor: |
100 |
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| Route: |
Oral: drinking water |
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| Target Organ / Critical Effect: |
Heart / Decreased weight |
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Brain / Decreased weight |
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| Species |
Effect Level |
Dose |
Experiment Length |
| Rat |
NOEL |
30 mg/kg/day |
90 days |
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| References |
| 1976 | Sauerhoff M.W,, W.H. Braun, J.C. Ramsey et al. 1976. Toxicological evaluation and pharmacokinetic profile of b-Hydroxypropionitrile in rats. J Toxicol Environ Health. 2(1): 31-44. |
| 1988 | U.S. EPA. 1988. Health and environmental effects document for Cyanohydrins. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC |
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