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Health Effects Assessment Summary (HEAST) for

Endrin

CAS: 000072-20-8

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)		 3E-4 mg/kg/day

Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Central nervous system / Convulsions
Liver / Lesions

Species Effect Level Dose Experiment Length
Dog NOEL 0.025 mg/kg/day 2 years

References
1969 Velsicol Chemical Corporation. 1969. MRID No. 00030198. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1991 U.S. EPA. 1991. Drinking water criteria document for Endrin. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Drinking Water, Washington, DC
1987 U.S. EPA. 1987. Health effects assessment for Endrin. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Emergency and Remedial Response, Washington, DC
1988 U.S. EPA. 1988. RfD/RfC Work Group.
Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].


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