EPA Home PageSuperfund Risk Assessment Home Page


Health Effects Assessment Summary (HEAST) for

Endosulfan

CAS: 000115-29-7

Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line





Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]: 6E-3 mg/kg/day
Uncertainty Factor: 100

Route: Oral: diet

Target Organ / Critical Effect: Whole body / Decreased weight gain
Kidney / Glomerulonephrosis
Blood vessel / Aneurysms

Species Effect Level Dose Experiment Length
Rat NOAEL 15 ppm 2 years

References
1989 Hoechst Celanese Corp. 1989. Endosulfan: 2-year feeding/oncogenicity study in rats. MRID No. 40256502, 42099502. HED Doc. No. 007937. Available from EPA. Write to FOI, EPA, Washington, DC 20460.
1993 U.S. EPA. 1993. RfD/RfC Work Group.


[ Risk Assessment Home ]
[ EPA Home | OSWER Home | Superfund Home ]
[ Search EPA | Search Superfund | Whats New | Contact Us ]
Horizontal Rule
URL: http://risk.lsd.ornl.gov/epa/heast/heast_select.htm
This page was last updated on: March 1, 2000
Site maintained by: Office of Emergency and Remedial Response
Hofmann.Lee@epamail.epa.gov
Horizontal Rule