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Health Effects Assessment Summary (HEAST) for

Disulfoton

CAS: 000298-04-4


Summary of HEAST Information on-Line

Subchronic and Chronic Toxicity
Chronic [RfD]:IRIS
Subchronic [RfD]:on-Line
Notes/Comments:on-Line






Subchronic and Chronic Toxicity (Other than Carcinogenicity)

Subchronic [RfD]:
(see comment)
4E-5 mg/kg/day

Uncertainty Factor: 1000

Route: Oral: diet

Target Organ / Critical Effect: Eye / Degeneration
Blood / Cholinesterase inhibition

Species Effect Level Dose Experiment Length
Rat LOAEL 0.04 mg/kg/day 2 years

References
1985 Mobay Chemical Company. 1985. MRID No. 00129456, 00146873, available from EPA, write to FOI, EPA, Washington, DC 20460.
1990 U.S. EPA. 1990. Health and environmental effects document for Disulfoton. Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington DC
1986 U.S. EPA. 1986. RfD/RfC Work Group.

Subchronic [RfD] Comments: The chronic oral RfD was adopted as the subchronic oral [RfD].



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